June 22, 2011 / 1:24 PM / 8 years ago

Patient Recruitment and Clinical Vendor Fees Top Trial Cost Drivers

The highest clinical trial cost drivers are patient recruitment costs and
vendor fees, according to a new study on clinical operations from Cutting
Edge Information.

    At 32% of trial budgets, the largest single driver of clinical costs --
patient recruitment -- has been a challenge for clinical development
teams for years. Although patient recruitment represents almost one-third
of clinical costs, few companies actually prepare for recruitment
expenses or implement best practices to accelerate the patient
recruitment process.

    Patient recruitment isn't the only driver of rising clinical costs.
Vendor fees and site recruitment are having a larger impact on clinical
expenditures today than in the past. The biggest single reason for issues
in these areas, say interviewed executives, is ever-increasing
competition for top investigators. An increase in the number of trials
across the board means that more and more companies want to attract the
best-performing CROs and sites, which drives higher prices. Likewise,
finding CROs and sites that are not recruiting against themselves by
running similar studies is proving challenging -- and thereby expensive.

    Cutting Edge Information's study, "Clinical Operations: Benchmarking
Per-Patient Trial Costs, Staffing and Adaptive Design," available at
surveyed 59 pharmaceutical, biotech and clinical service organizations. 

    On average, the findings found that the largest clinical cost drivers
 * Patient recruitment: 32%
 * Vendor fees: 25%
 * Site recruitment:
 * CTMS and other technology: 12%:
 * Site retention: 8%:
 * Data
management and validation: 7%
 * Patient retention: 2%

    "The impending patent cliff is putting an incredible strain on drug
manufacturers to develop new treatments," said Jason Richardson,
president at Cutting Edge Information. "You can imagine the challenge
that R&D teams have guiding these pipeline products from discovery to
market in an age when clinical trial costs are at an all-time high."

    Cutting Edge Information developed "Clinical Operations: Benchmarking
Per-Patient Trial Costs, Staffing and Adaptive Design" to provide best
practices and strategies that help clinical development teams to improve
trial efficiency, cut costs and earn products more time on the market to
recoup expenses. 

    The new study provides up-to-date benchmarks to help development teams
increase clinical trial efficiency. Clinical trial costs and staffing
metrics are presented across several therapeutic areas in all phases of


Elio Evangelista
+1 919-403-6583 

Copyright 2011, Market Wire, All rights reserved.

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