NEW YORK (Reuters Health) - The number of drugs dispensed to U.S. minors has dropped slightly over the past decade, bucking the rise in prescriptions to adults, according to a government report out Monday.
Antibiotics use fell by 14 percent, suggesting efforts to curb rampant overuse of the drugs “may be working,” researchers from the U.S. Food and Drug Administration (FDA) write in the journal Pediatrics.
Experts say antibiotics are commonly used to treat infections caused by viruses, although they only work against bacteria. That has fueled the growth of drug-resistant superbugs.
The new report also found an uptick in the use of some drugs in children, with stimulants for attention deficit hyperactivity disorder, or ADHD, leading the pack.
From 2002 to 2010, the use of ADHD drugs grew by 46 percent — or some 800,000 prescriptions a year. The top drug dispensed to adolescents was the stimulant methylphenidate, also known as Ritalin, with more than four million prescriptions filled in 2010.
“What the article is suggesting is that the number of children that we are treating for attention deficit disorder has gone up,” said Dr. Scott Benson, a child and adolescent psychiatrist and a spokesperson for the American Psychiatric Association.
“For the most part I think the overall increase reflects a reduction in the stigma,” he told Reuters Health. “It used to be, ‘You’re a bad parent if you can’t get your child to behave, and you’re a doubly bad parent if you put them on medicine.’”
Dr. Lawrence Diller, a behavioral pediatrician who has written extensively about ADHD, was more critical of the rise in stimulant prescriptions, noting that the U.S. is far ahead of other countries in its use of the drugs.
“You have to look at how our society handles school children’s problems. It’s clear that we rely much, much more on a pharmacological answer than other societies do,” Diller said. “The medicine is overprescribed primarily, but under-prescribed for certain inner-city groups of children.”
A report in the New York Times last Sunday said stimulant use is becoming a commonly used study drug even among high schoolers, with healthy students easily fooling their doctors into prescribing the coveted drugs.
“There is no objective test, so obtaining the medications is relatively easy,” said Diller.
The new findings are based on data from healthcare research firm IMS Health and do not include drugs given at hospitals.
Overall, there were 263 million filled prescriptions to minors in 2010, down seven percent since 2002. After taking population changes into account, that corresponds to a nine-percent drop; by contrast, adult prescriptions rose by 11 percent.
Prescription drugs classes that showed marked dips among children included allergy medicines, cough and cold drugs, painkillers, and antidepressants.
Apart from ADHD drugs, asthma medicine and birth control pills also showed increases.
The FDA said it could not explain the reasons behind the changes.
The agency also looked at an acid reflux drug called lansoprazole (sold as Prevacid) due to concerns about efficacy and safety in infants.
The medication is not indicated for children younger than one, and studies show it has no effect in that age group. Yet doctors wrote 358,000 prescriptions for the drug to babies under one in 2010.
Dr. Eric Hassall, a pediatric gastroenterologist at the California Pacific Medical Center, said the number reflects rampant overuse of acid drugs in infants.
“These drugs work very well when they are prescribed for the right indication,” he told Reuters Health. “But in infants they are very seldom indicated.”
He added that stomach acid is the first defense against many infections and blocking it even for part of the day will raise children’s risk of pneumonia and stomach infections.
“My concern is that we are unnecessarily exposing infants to infectious and nutritional complications,” Hassall said. “Doctors are too quick to prescribe and parents are very quick to demand, and this is of course driven by consumer advertising.”
“I would advise parents that if their child is growing and developing normally despite spitting up, they should resist the urge to give the child a medical diagnosis and administer prescription medications,” he added. “If their child is excessively irritable or otherwise unwell, they should seek medical consultation.”
SOURCE: bit.ly/HjQ8dI Pediatrics, online June 18, 2012.