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Ultragenyx seizure drug fails mid-stage study

(Reuters) - Ultragenyx Pharmaceutical Inc said its drug to treat patients with seizures did not meet the main goal in a mid-stage study, sending its shares down 6.2 percent in after-market trading on Wednesday.

The company said the study did not show statistical significance in reducing the frequency of seizures among patients treated with the drug compared to a placebo, during a eight week treatment period.

Ultragenyx’s experimental treatment for mucopolysaccharidosis — a rare genetic, metabolic disorder when the body is unable to breakdown GAGs, a kind of complex carbohydrate — is in its late stage.

The company’s other rare and ultra-rare disease treatments are in its mid-stages.

Reporting by Akankshita Mukhopadhyay in Bengaluru; Editing by Shounak Dasgupta

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