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US STOCKS-S&P, Dow futures rise after Moderna says vaccine 94.5% effective

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* Moderna jumps after COVID-19 vaccine update; Pfizer falls

* Banks, airlines, cruise operators rally

* Stay-at-home winners Netflix, Amazon fall

* Futures: Dow up 1.62%, S&P up 1.07%, Nasdaq flat (Adds comment, details; Updates prices)

Nov 16 (Reuters) - Futures tracking the S&P 500 and the Dow rose on Monday after Moderna became the second U.S. company in a week to report positive results from its COVID-19 vaccine trial, raising hopes of a quicker economic recovery from a pandemic-led recession.

Moderna Inc soared 15% in premarket trading as it said its experimental vaccine was 94.5% effective in preventing COVID-19 based on interim data from a late-stage trial.

Nasdaq 100 futures fell as investors again sold some of this year’s “stay-at-home” winners, although gains of about a percent for Dow and S&P 500 futures were less stellar than those after a similar release from Pfizer Inc a week ago.

Travel-related stocks including United Airlines Holdings Inc , American Airlines Group Inc, Carnival Corp and Norwegian Cruise Line Holdings Ltd, which have lost more than half their market capitalization this year due to the pandemic, jumped between 7% and 10%.

“This enables managers to now more broadly expose their portfolios to new pockets of growth,” said Thomas Hayes, managing member at Great Hill Capital Llc in New York.

“You could potentially have a little bit of profit-taking in the morning, but on balance there’s not much to sell in this news in the fact that most (fund) managers went into the election flatfooted and now they’ve got to play catch up in the year end.”

Bets of a working COVID-19 vaccine fueled gains on Wall Street last week, helping investors look past surging coronavirus cases across the United States which topped the 11 million mark, just over a week after hitting 10 million.

The benchmark S&P 500 and the small-cap Russell 2000 ended Friday at record closing highs, while the technology-heavy Nasdaq fell slightly.

At 7:50 a.m. ET, Dow e-minis were up 475 points, or 1.62%, S&P 500 e-minis were up 38.25 points, or 1.07%, and Nasdaq 100 e-minis were down 2.5 points, or nearly flat.

Big U.S. banks gained between 2.5% and 3.3%, building on gains from last week, while Boeing Co and Chevron Corp jumped more than 3%.

Better-than-expected factory output data from China also bolstered optimism about a rebound from a coronavirus-induced slump, pushing global stocks closer to record highs on Monday.

Among other stocks, Simon Property Group Inc jumped 10.2% after the biggest U.S. mall operator cut its purchase price for an 80% stake of rival Taubman Centers Inc, as the virus outbreak upends the retail industry sector.

Johnson & Johnson gained 1.5% after launching a new large-scale study to test a two-dose regimen of its experimental COVID-19 vaccine. (Reporting by Medha Singh and Shivani Kumaresan in Bengaluru; Editing by Sagarika Jaisinghani and Shounak Dasgupta)