Edition:
United States

Shire PLC (SHP.L)

SHP.L on London Stock Exchange

3,735.00GBp
23 Nov 2017
Change (% chg)

-17.00 (-0.45%)
Prev Close
3,752.00
Open
3,734.00
Day's High
3,771.50
Day's Low
3,703.00
Volume
1,294,503
Avg. Vol
2,925,241
52-wk High
5,067.00
52-wk Low
3,435.50

Latest Key Developments (Source: Significant Developments)

Shire names Thomas Dittrich as CFO
Monday, 20 Nov 2017 08:01am EST 

Nov 20 (Reuters) - Shire Plc :Shire Plc <<>> says Thomas Dittrich will join company as chief financial officer​.Shire Plc <<>> says Thomas Dittrich will assume his role as CFO in early 2018 following a transition period from his current employer​.  Full Article

Omega Advisors dissolves share stake in Carrizo Oil & Gas, ups in Shire PLC
Tuesday, 14 Nov 2017 12:53pm EST 

Nov 14 (Reuters) - Omega Advisors Inc::Omega Advisors Inc dissolves share stake in Carrizo Oil & Gas Inc - SEC Filing‍​.Omega Advisors Inc raises share stake in Shire PLC by about 31 percent to 653,977 sponsored ADRs.Omega Advisors Inc - Change in holdings are as of Sept 30, 2017 and compared with the previous quarter ended as of June 30, 2017.  Full Article

Shire says CHMP recommends EU marketing authorization for ADYNOVI [Antihemophilic Factor (Recombinant), PEGylated]
Monday, 13 Nov 2017 01:00am EST 

Nov 13 (Reuters) - SHIRE PLC ::CHMP RECOMMENDS EU MARKETING AUTHORIZATION FOR ADYNOVI [antihemophilic factor (recombinant), pegylated] FOR ADULTS AND ADOLESCENTS WITH HEMOPHILIA A​.  Full Article

Third Point takes share stake in Macerich, dissolves share stake in Humana
Thursday, 9 Nov 2017 05:28pm EST 

Nov 9 (Reuters) - ‍THIRD POINT LLC​:Third Point LLC dissolves Class A share stake in Charter Communications Inc <<>> - SEC filing.Third Point LLC dissolves share stake in Hewlett Packard Enterprise.Third Point LLC dissolves share stake in Humana Inc.Third Point LLC raises share stake in Alibaba Group Holding Ltd by about 47 percent to 6.6 million Sponsored ADS.Third Point LLC dissolves share stake in General Dynamics Corp.Third Point LLC takes share stake of 1.2 million Sponsored ADR in Shire Plc.Third Point LLC cuts share stake in T-Mobile US Inc by about 27 percent to 3.9 million shares.Third Point LLC cuts share stake in Time Warner Inc by about 27 percent to 2.8 million shares.Third Point LLC takes share stake of 1.7 million shares in Macerich Co.Third Point LLC takes share stake of 2.8 million shares in Marathon Petroleum Corp.Third Point LLC reports share stake of 750,000 shares in Altaba Inc.‍Third Point LLC - Change in holdings are as of Sept 30, 2017 and compared with the previous quarter ended as of June 30, 2017.  Full Article

Shire receives European approval for label extension of firazyr for symptomatic treatment
Thursday, 26 Oct 2017 02:01am EDT 

Oct 26 (Reuters) - SHIRE PLC ::SHIRE RECEIVES EUROPEAN APPROVAL FOR LABEL EXTENSION OF FIRAZYR (ICATIBANT INJECTION) FOR THE SYMPTOMATIC TREATMENT OF ACUTE HAE ATTACKS IN PAEDIATRIC PATIENTS.FIRAZYR WILL BE AVAILABLE FOR USE IN PAEDIATRIC PATIENTS IN EUROPE BEGINNING IN Q4​.  Full Article

Shire receives orphan drug designation for gene therapy candidate for treatment of Hemophilia A
Wednesday, 25 Oct 2017 07:00am EDT 

Oct 25 (Reuters) - Shire Plc :SHIRE RECEIVES ORPHAN DRUG DESIGNATION FOR GENE THERAPY CANDIDATE SHP654 (BAX 888) FOR THE TREATMENT OF HEMOPHILIA A.‍SHP654 INVESTIGATIONAL NEW DRUG (IND) APPLICATION ACCEPTED BY FDA​.RECEIVES ORPHAN DRUG DESIGNATION FOR GENE THERAPY CANDIDATE SHP654 (BAX 888) FOR TREATMENT OF HEMOPHILIA A​.‍REGULATORY AGENCY ALSO GRANTED SHIRE INVESTIGATIONAL NEW DRUG (IND) STATUS FOR SHP654​.ALSO RECEIVED FDA CLEARANCE FOR IND APPLICATION IT SUBMITTED EARLIER THIS YEAR TO INITIATE A GLOBAL MULTI-CENTER STUDY​.‍COMPANY ANTICIPATES THAT SHP654 PHASE 1/2 STUDY WILL BEGIN BY END OF 2017​.  Full Article

Shire says EU regulator backs new formulation of blood cancer treatment
Friday, 13 Oct 2017 01:03am EDT 

Oct 13 (Reuters) - SHIRE PLC ::NEW FORMULATION OF ONCASPAR® (PEGASPARGASE) RECEIVES POSITIVE CHMP OPINION IN EUROPE FOR PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA.EMA'S CHMP ADOPTED A POSITIVE OPINION RECOMMENDING MARKETING AUTHORIZATION FOR LYOPHILIZED ONCASPAR​.  Full Article

Shire and Shionogi announce positive topline results for Intuniv ​
Wednesday, 20 Sep 2017 02:00am EDT 

Sept 20 (Reuters) - SHIRE PLC ::‍SHIRE AND SHIONOGI ANNOUNCE POSITIVE TOPLINE RESULTS FOR INTUNIV EVALUATED IN PHASE 3 CLINICAL TRIAL IN ADULTS WITH ADHD​.  Full Article

Shire receives FDA fast track designation for SHP607
Tuesday, 12 Sep 2017 07:00am EDT 

Sept 12 (Reuters) - Shire Plc :SHIRE RECEIVES FDA FAST TRACK DESIGNATION FOR SHP607 FOR THE PREVENTION OF CHRONIC LUNG DISEASE IN EXTREMELY PREMATURE INFANTS.‍UNITED STATES FDA GRANTED FAST TRACK DESIGNATION FOR SHP607 FOR PREVENTION OF CHRONIC LUNG DISEASE IN EXTREMELY PREMATURE INFANTS​.IS CURRENTLY CONDUCTING A FIVE-YEAR OBSERVATIONAL LONG-TERM OUTCOMES STUDY OF PATIENTS WHO HAD BEEN ENROLLED IN PHASE 2 STUDY..‍FOLLOWING PHASE 2 STUDY RESULTS, INITIATED DISCUSSIONS WITH REGULATORY AUTHORITIES IN U.S, EUROPE AND JAPAN TO DISCUSS APPROPRIATE REGULATORY REVIEW PATHWAY FOR SHP607​.PROCESS OF DEVELOPING A PHASE 2B/3 CLINICAL TRIAL SHP607 TARGETING A PRIMARY ENDPOINT FOCUSED ON CHRONIC LUNG DISEASE IN EXTREMELY PREMATURE INFANTS​.  Full Article

Shire announces collaboration with Microhealth to address needs of hemophilia A and B patients with inhibitors
Friday, 25 Aug 2017 07:00am EDT 

Aug 25 (Reuters) - Shire Plc :Shire announces collaboration with Microhealth to address unique needs of hemophilia A and B patients with inhibitors.  Full Article

UPDATE 1-Britain's FTSE recoups early losses as cyclicals recover

* Mediclinic, Spire shares fall after takeover talks fall through