‘The right path’ - Chile defends Sinovac use amid fresh efficacy questions

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SANTIAGO, April 11 (Reuters) - Chilean authorities on Sunday backed the country’s widespread use of the COVID-19 vaccine manufactured by Chinese firm Sinovac after China’s top disease official appeared to make conflicting statements about its efficacy.

Gao Fu, the director of the Chinese Centers for Disease Control and Prevention, told a conference in the Chinese city of Chengdu on Saturday that the country was considering mixing COVID-19 vaccines since currently available vaccines "don't have very high rates of protection." read more

He later said in an interview with statemedia that his comments were "completely misunderstood."

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Available data shows Chinese vaccines lag behind others including Pfizer (PFE.N) and Moderna (MRNA.O) in terms of efficacy, but require less stringent temperature controls during storage.

The COVID-19 vaccine developed by China's Sinovac (SVA.O) was found to be just over 50% effective in reducing infection in Brazilian clinical trials. A real-world study of vaccination and contagion data by the University of Chile suggested last week the vaccine was 54% effective in reducing infection.

Chile paid $3.5 million to host a clinical trial of the vaccine and has also ordered 60 million doses to be administered to its 18 million-strong population over three years.

The country has largely relied on the Sinovac vaccine, along with smaller numbers of Pfizer's equivalent drug, to roll out one of the world's fastest vaccination campaigns, so far inoculating 4.6 million people with two doses and 7.2 million with one. read more

Chile also signed deals for the supply of vaccines from western drugmakers Johnson & Johnson (JNJ.N) and AstraZeneca (AZN.L) but these are yet to materialise because of supply bottlenecks.

On Sunday, Chilean science minister Andres Couve said it was important to focus on the data and the vaccine's effectiveness in reducing illness that required medical treatment or being hospitalized or dying, which it achieved in the Brazilian study in 83.7% and 100% of cases respectively. read more

He said Chile's health ministry will shortly publish a real world study on the effectiveness of both vaccines rolled out in its population and appealed to Chileans to continue to participate in the vaccination programme.

Heriberto Garcia, director of Chile's Public Health Institute which greenlighted CoronaVac's emergency roll-out, said people should not pay attention to headlines. read more

"The University of Chile study and the study the health ministry will release say the same thing: the number of people who fall ill and are hospitalized has decreased," he told local newspaper La Tercera. "We are going down the right path."

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Reporting by Aislinn Laing; editing by Diane Craft

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