U.S. starts enrollments in trial testing smaller dosage of monkeypox vaccine

Monkeypox vaccination drive
A man receives a dose of the Jynneos monkeypox vaccine as part of DC Health's first vaccination drive in Washington, U.S., June 28, 2022. REUTERS/Gavino Garay

Sept 8 (Reuters) - The National Institutes of Health said on Thursday it had started enrollments in a trial testing an alternative method of administering Bavarian Nordic's monkeypox vaccine, Jynneos, which requires smaller dosages.

U.S. health regulators last month authorized injecting the shot intradermally in adults, meaning between layers of the skin rather than below the skin, in an effort to stretch out low vaccine supplies. read more

This alternative intradermal dosing regime will allow health care providers to administer up to five times the number of vaccine doses per vial of shot.

The NIH trial will enroll 200 people between 18 and 50 years of age, who have not been previously vaccinated across eight U.S. research sites.

Nearly 20,000 cases of monkeypox have been reported in the United States since May when a large global outbreak began in countries where the virus is not endemic, according to government data.

Reporting by Khushi Mandowara; Editing by Vinay Dwivedi

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